U.S. cancer death rates have fallen by 34% since 1991, saving an estimated 4.5 million lives, according to the American Cancer Society’s Cancer Statistics, 2025. However, the report also highlights a troubling trend: cancer incidence rates are increasing sharply among women, especially those under 50. Women in this age group now experience cancer at rates 82% higher than men, with rising cases of lung, breast, uterine, and oral cancers.
Despite significant progress in cancer mortality, disparities persist. Native Americans are two to three times more likely than White Americans to die from certain cancers, and Black Americans face disproportionately higher death rates from prostate, uterine, and cervical cancers. “Expanding equitable access to screenings and treatment is essential to saving lives and addressing these inequalities,” said Dr. Wayne A. I. Frederick, interim CEO of ACS.
For South Durham families, the report underscores the importance of early detection and preventive care. Regular screenings, understanding family health histories, and advocating for equitable healthcare access are crucial. Stay informed on how these trends impact our community by subscribing to the SoDu We Like Local News? newsletter.

